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EC number: 233-828-8 | CAS number: 10377-66-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Toxicity to other aquatic organisms
Administrative data
- Endpoint:
- toxicity to other aquatic vertebrates
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study conducted on read-across material
- Remarks:
- Meets generally accepted scientific standards. The read-across from MnSO4 to Mn(NO3)2 is justified on the following basis: both substances are very soluble in water hence bioavailable and both will release Mn2+ ions. Therefore, from an ecotoxicity standpoint, the nitrate or sulphate anions are not considered to have any influence on the effective toxicity of Mn2+ or any toxicity in their own right, so the anions can be disregarded. Therefore any effect will be related to the Mn2+ cation, and the data from MnSO4 ecotoxicity tests is regarded as a suitable surrogate for read-across
- Justification for type of information:
- See the read-across report attached in Section 13.
Cross-reference
- Reason / purpose for cross-reference:
- other: Read-across target
Reference
- Endpoint:
- toxicity to other aquatic vertebrates
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study conducted on read-across material
- Justification for type of information:
- See the read-across report attached in Section 13.
- Reason / purpose for cross-reference:
- read-across source
- Duration:
- 10 d
- Dose descriptor:
- EC50
- Effect conc.:
- 20.8 mg/L
- Conc. based on:
- other: Mn
- Basis for effect:
- mortality
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxicity of manganese and zinc to Boreal toad tadpoles (Bufo boreas)
- Author:
- Davis H, Brinkman S and McIntyre M
- Year:
- 1 998
- Bibliographic source:
- Federal aid project #F-243R-5, , Colorado Division of Wildlife, Fort Collins, Colorado
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- GLP compliance:
- not specified
Test material
- Reference substance name:
- manganese sulphate
- IUPAC Name:
- manganese sulphate
- Details on test material:
- - Name of test material (as cited in study report): Manganese sulphate monohydrate
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test organisms
- Test organisms (species):
- Bufo boreas
Study design
- Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 10 d
Results and discussion
Effect concentrations
- Duration:
- 10 d
- Dose descriptor:
- EC50
- Effect conc.:
- 20.8 mg/L
- Conc. based on:
- other: Mn
- Basis for effect:
- mortality
Any other information on results incl. tables
Manganese concentrations were stable throughout the 24 hour period between renewals.
Mortality did not occur in manganese exposures of 10 mg Mn/L or less. In the 50 mg/L exposure, 40% mortality occurred by 96 hours leading to complete mortality by 168 hours. Mortality in the 100 mg/L exposure started as soon as 24 hours and resulted in complete mortality by 96 hours. The 96 and 168 hour LC50 were 42.3 and 20.8 mg Mn/L respectively
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- The LC50 was 42.3 mg Mn/L. The read-across from MnSO4 to Mn(NO3)2 is justified on the following basis: both substances are very soluble in water hence bioavailable and both will release Mn2+ ions. Therefore, from an ecotoxicity standpoint, the nitrate or sulphate anions are not considered to have any influence on the effective toxicity of Mn2+ or any toxicity in their own right, so the anions can be disregarded. Therefore any effect will be related to the Mn2+ cation, and the data from MnSO4 ecotoxicity tests is regarded as a suitable surrogate for read-across
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