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EC number: 276-736-3
CAS number: 72623-85-9
A complex combination of hydrocarbons obtained by treating light vacuum gas oil, heavy vacuum gas oil, and solvent deasphalted residual oil with hydrogen in the presence of a catalyst in a two stage process with dewaxing being carried out between the two stages. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and produces a finished oil having a viscosity of approximately 112cSt at 40°C. It contains a relatively large proportion of saturated hydrocarbons.
Table 1. Micronucleus Tests of Mineral Hydrocarbons in Female CD-1 Mice
20 mg/kg cyclophosphamide
**Significantly different from control at p<0.01
Positive control tested at 24 hours only
Table 2. Micronucleus Tests of Mineral Hydrocarbons in Male CD-1 mice
In a CD-1 mouse bone marrow micronucleus
assay, male and female mice were given a single intraperitoneal
injection of 5 different paraffin oils in corn oil vehicle at doses of
0, 1.0, 2.5, or 5.0 g/kg. Bone marrow cells were harvested at 24, 48,
and 72 hours post-dosing. One animal did not survive to scheduled
sacrifice, but there were no gross signs of toxicity. The micronucleus
frequency was significantly greater than the concurrent negative control
in bone marrow cells of male mice given 5.0 g/kg at 48 hours
post-dosing, but the negative control was unusually low in this
instance, and therefore this result is not considered significant.
This study received a Klimisch score of 1
and is considered reliable without restriction because it was carried
out according to OECD Guideline 474.
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