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EC number: 230-528-9 | CAS number: 7173-62-8
The safety assessment according to Annex 1 does not indicate the need to investigate further the effects on aquatic organisms. Therefore no chronic fish testing is justified.
According to Annex IX, 9.1.6 to the REACH Regulation long-term toxicity testing with fish shall be proposed only if the CSA indicates the need to investigate further the effects on aquatic organisms. However, as the CSA does not indicate the need for further testing of vertebrates long-term toxicity testing with fish is waived. Waiving is supported by the low bioaccumulation potential of the substance and the fact that the acute toxicity data demonstrate that fish are less sensitive to the linear alkyl diamines compared to daphnia and algae.
For the calculation of the PNECaquatic it is considered unlikely that fish toxicity will be critical for alkyl-1,3-diaminopropanes. Hence any additional toxicity testing with fish will not add scientific value to the ecotoxicity profile of the alkyl-1,3-diaminopropanes other than for obtaining a lower assessment factor. It is therefore concluded that for scientific reasons and in accordance to REACH legislation further testing on fish has to be avoided for reasons of animal welfare.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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