Registration Dossier

Ecotoxicological information

Long-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The safety assessment according to Annex 1 does not indicate the need to investigate further the effects on aquatic organisms. Therefore no chronic fish testing is justified.

Key value for chemical safety assessment

Additional information

According to Annex IX, 9.1.6 to the REACH Regulation long-term toxicity testing with fish shall be proposed only if the CSA indicates the need to investigate further the effects on aquatic organisms. However, as the CSA does not indicate the need for further testing of vertebrates long-term toxicity testing with fish is waived. Waiving is supported by the low bioaccumulation potential of the substance and the fact that the acute toxicity data demonstrate that fish are less sensitive to the linear alkyl diamines compared to daphnia and algae.

For the calculation of the PNECaquatic it is considered unlikely that fish toxicity will be critical for alkyl-1,3-diaminopropanes. Hence any additional toxicity testing with fish will not add scientific value to the ecotoxicity profile of the alkyl-1,3-diaminopropanes other than for obtaining a lower assessment factor. It is therefore concluded that for scientific reasons and in accordance to REACH legislation further testing on fish has to be avoided for reasons of animal welfare.