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Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

For the representatives of the group members (Fe3O4, Fe2O3 and FeOOH) no skin sensitisation potential was found in Maurer optimisation tests with members of the Category.


Migrated from Short description of key information:
For skin sensitisation a Maurer optimisation test was conducted for Fe3O4, Fe2O3 and FeOOH as surrogates for (Fe,Mn)3O4 - all three compounds are not irritant to skin and eye, and have no skin sensitizing potential (for further details see category justification).

Justification for selection of skin sensitisation endpoint:
scientifically acceptable and sufficient documented

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available
Additional information:

All group members of the iron oxide group are insoluble in water and inert. A sensitisation of the respiratory tract is not expected. This statement is supported by the human evidence on Fe2O3, Fe3O4, FeOOH and manganese oxides where such an effect was not described in the scientific literature.


Migrated from Short description of key information:
no data

Justification for classification or non-classification

Based on the available data a classification is not justified.

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