Registration Dossier
Registration Dossier
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EC number: 203-453-4 | CAS number: 107-02-8
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Freshwater fish
Pimephales promelas: 96 h LC50=0.0195 mg/l
Marine water fish
Pleuronectes platessa: 96 h LC50=0.179 mg/l
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.019 mg/L
Marine water fish
Marine water fish
- Effect concentration:
- 0.179 mg/L
Additional information
1. European Union Risk Assessment Report of Acrolein (EU, 2001)
Fresh water
The short term LC50-values for freshwater fish range from 14 to 250 µg/l. For Leuciscus idus melanotus two LC50-values (250 and 2500 µg/l) were parallelly derived in two different German laboratories according to the same method. In the view of the results from the other tests the highest value of 2500 µg/l is considered to be an outlier.”
The effect values of the tests considered to be most reliable were in the range from 14 to 90 µg/l, based on measured concentrations.
Marine fish
Short-term toxicity data for two marine fish species are available in EU (2001). LC50-values are reported as 56 and 240 µg/l. The data for the first test are obtained from a review. For the 2nd test the complete test report was available and therefore this test is considered to be more reliable. To avoid losses of acrolein from the test solution, normal aeration was dispensed with.
Supplement to 1. European Union Risk Assessment Report of Acrolein (EU, 2001)
Marine fish
A review and reevaluation of the 2nd test shows that the LC50 is 179 µg/l. The value was calculated as geometric mean of 100µg/l (EC0) and 320 µg/l (EC100).
2. Agreement with further international Reports and Studies published after finalisation of the EU Risk Assessment Report 2001
WHO (2002): Short-term LC50s for freshwater fish range from 14 to 250 μg/litre. For marine fish, LC50s of 56–240 μg/litre have been reported.
3. Substantial disagreements in comparison to further international Reports to European Union Risk Assessment Report 2001
None
4. Additional aspects in further international Reports
None
5. Additional information in newer Studies, not included in the European Union Risk Assessment Report 2001 or further cited international reports
None
6. Conclusions
For freshwater fish the most reliable LC50-values were considered to be in the range of 14 to 90 µg/l, all based on measured concentrations. The most reliable LC50 for marine fish species is 179 µg/l (recalculation (geometric mean) from test results EC0 100µg/l and EC100 320µg/l).
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