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Administrative data

Description of key information

The only available acute toxicity data is a Reliability 1 acute oral toxicity test in the rat, conducted in accordance with OECD 423 (Acute Toxic Class method) in male and female rats. The LD50 was determined to be in the range 200-2000 mg/kg bw. Clinical signs included reduced motility, ataxia, reduced muscle tone, and dyspnoea

Key value for chemical safety assessment

Additional information

Only one acute toxicity study is available.

Justification for classification or non-classification

On the basis of an acute oral LD50 in the range 200 -2000 in the rat, determined in a test following the Acute Toxic Class method, trichloro(3-chloropropyl)silane is classified R22 according to the criteria of EU Directive 67/548/EEC and Acute Toxic 4 (oral) under Regulation 1272/2008.