Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-669-1 | CAS number: 123-99-9
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
LC50 (96h) > 16 mg/L (meas. geom. mean)
Key value for chemical safety assessment
Additional information
No study is available on the short-term toxicity of azelaic acid to fish. However, a study investigating the short-term toxicity to fish of decanoic acid is available and used as read across based on a category approach. Both substances are structurally and compositionally related. Due to an increasing toxicity with increasing chain length from octanoic acid (C8) to lauric acid (C12) for fish, the study for decanoic acid (C10) represents a worst case for azelaic acid (C9), probably overestimating the toxicity for azelaic acid.
In this study (Ministry of the Environment of Japan, 1999) with Oryzias latipes conducted according to OECD 203 an LC50 >16 mg/L (meas. geom. mean) was determined. No mortality was observed in the range of the tested concentration (16 mg/L meas. geom. mean).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
