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PBT assessment

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PBT assessment: overall result

valeryl chloride SIP
Type of composition:
boundary composition of the substance
State / form:
Reference substance:
valeryl chloride SIP
PBT status:
the substance is not PBT / vPvB

Valeryl chloride (CAS 638 -29 -9) rapidly hydrolyzes (T1/2 < 12 hours) and decomposes in water into the main products valeric acid (CAS 109 -52 -4) and HCl (CAS 7647-01-0). The PBT/vPvB criteria do not apply to inorganic substances, HCl is not assessed with regard to PBT/vPvB properties; therefore, the PBT/vPvB assessment is mainly based on data for valeryl chloride and its organic hydrolysis product valeric acid (CAS 109 -52 -4).

Since valeric acid is readily biodegradable (according to OECD criteria) it should be regarded as not P/vP. The substance is not B/vB since valeryl chloride itself and its hydrolysis product valeric acid have a log Kow less than 3 (see IUCLID chapter 4.7).

Due to the rapid hydrolysis of the parent compound valeryl chloride (CAS 638 -29 -9) and in absence of chronic toxicity data for the compound itself, the assessment of T properties is based on the hydrolysis product valeric acid (CAS 109 -52 -4). No chronic toxicity data are availabe. However, valeric acid is not T since the lowest available acute value is >> 0.1 mg/L (Algae: 72 -h EC50: 31.3 mg/L, Read-across Analysis, QSAR Toolbox v4.4) and the substance holds no relevant classification.

In conclusion, the parent compound valeryl chloride (CAS 638 -29 -9) is considered to be neither PBT nor vPvB, based on the available data for the hydrolysis product valeric acid (CAS 109 -52 -4).