Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 248-258-5
CAS number: 27138-31-4
Short description of key information on bioaccumulation potential result: A study was performed to investigate the metabolism of the14C radiolabelled test substance DEGDB (diethylene glycol dibenzoate CAS no.: 120-55-8) when orally dosed to male and female Sprague Dawley (CD) rats (HLS 2000, VCL 320/993327). The study was conducted to EU and to OECD test guidelines and to GLP. Virtually all of single oral doses of 50 and 750 mg/kg of ring [U-14C phenyl] DEGDB administered to the rats were absorbed metabolised and excreted in the urine within 24 hours of administration. DEGDB was metabolised via hydrolysis of the ester bonds to benzoic acid; this free acid was then conjugated with either glycine (major pathway) or glucuronic acid (minor pathway) prior to excretion.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again