N-isopropyl-N'-phenyl-p-phenylenediamine

Sensitisation data (human)

Administrative data

Endpoint:

sensitisation data (humans)

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: limited but acceptable documented study report

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1978

Materials and methods

Type of sensitisation studied:

skin

Study type:

study with volunteers

Principles of method if other than guideline:

other: modified Draize skin sensitization study

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

N-isopropyl-N'-phenyl-p-phenylenediamine

EC Number:

202-969-7

EC Name:

N-isopropyl-N'-phenyl-p-phenylenediamine

Cas Number:

101-72-4

Molecular formula:

C15H18N2

IUPAC Name:

N1-phenyl-N4-(propan-2-yl)benzene-1,4-diamine

Details on test material:

Santoflex IP

Method

Type of population:

general

Route of administration:

dermal

Results and discussion

Results of examinations:

12/82 volunteers with positive skin reactions

Any other information on results incl. tables

Twelve subjects of 82 patched with Santoflex IP were deemed sensitized