Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: short report

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1978
Report date:
1978

Materials and methods

Principles of method if other than guideline:
500 mg/animal were applied onto the ear, washing of the ear; post observation period: 7 days
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Zinc ferrite brown spinel
EC Number:
269-103-8
EC Name:
Zinc ferrite brown spinel
Cas Number:
68187-51-9
Molecular formula:
ZnFe2O4
IUPAC Name:
Zinc ferrite brown spinel
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Test animals

Species:
rabbit
Strain:
New Zealand White

Test system

Type of coverage:
semiocclusive
Vehicle:
not specified
Controls:
not required
Amount / concentration applied:
undiluted
Duration of treatment / exposure:
24 hour(s)
Observation period:
7 days
Number of animals:
2

Results and discussion

In vivo

Results
Irritation parameter:
overall irritation score
Basis:
mean
Time point:
other: after removal, 2d, 7 d
Score:
0
Max. score:
8
Remarks on result:
other: no findings at any time point

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information
Executive summary:

500 mg/animal were applied onto the ear, washing of the ear; post observation period: 7 days

result: not irritating

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