Registration Dossier

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: No data about guideline followed

Data source

Reference
Reference Type:
other: book
Title:
Summary Tables of Biological Tests
Author:
National Research Council Chemical-Biological Coordination Center
Year:
1953
Bibliographic source:
"Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. Vol. 5, Pg. 340, 1953.

Materials and methods

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified
Details on test animals and environmental conditions:
no data

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
propylene glycol
Details on exposure:
no data
Doses:
no data
No. of animals per sex per dose:
five animals were tested but no data on sex or doses is available
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD0
Effect level:
>= 500 mg/kg bw
Based on:
act. ingr.
Mortality:
No mortality observed in any of the 5 animals tested.
Clinical signs:
Details of toxic effects not reported other than lethal dose value
Body weight:
No data
Gross pathology:
No data
Other findings:
No data

Applicant's summary and conclusion

Conclusions:
The application of 500 mg/Kg bw did not produce mortality in this study in any of the 5 animals tested.
Executive summary:

The data published reports no mortality on 5 mouse tested at 500 mg/Kg by intraperitioneal route. Details of toxic effects not reported other than lethal dose value. No data on sex, strains, or body weight of animals are provided.