Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 266-582-5 | CAS number: 67124-09-8
The test material is not acutely toxic.
Acute toxicity: oral (OECD TG 401)
In an acute oral toxicity study, fasted Sprague-Dawley strain Albino rats (five male and five female) were given a single oral dose of undiluted test material at a dose level of 5000 mg/kg bw and observed for 14 days (Costello, 1982).
All animals appeared ruffled up to 3 h after treatment; they appeared oily and dirty after 24h, but appeared normal thereafter. One male rat died on day 2 with the remaining animals exhibited a discharge around the eyes and nose. They appeared essentially recovered after 72 h and continued to appear normal throughout the remainder of the observation period. Gross pathologic examination revealed nothing remarkable.
Acute toxicity: dermal (OECD TG 434)
This substance does not show adverse toxicity effects via the dermal route of exposure in rabbits when tested in accordance with OECD 434 (Morris, 1991). The treated skin surface of animals showed irritation after test material removal, but there were no other clinical signs of toxicity or behavioral changes over the 15 day observation period. Macroscopic examination of all animals at the end of the study did not reveal any changes that were considered to have arisen as a result of treatment. The rabbit dermal LD50 is greater than 2000 mg/kg.
In accordance with EU CLP (Regulation (EC) No. 1272/2008), classification of this substance is not required for acute toxicity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Close Do not show this message again