Registration Dossier
Registration Dossier
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EC number: 295-445-2 | CAS number: 92045-63-1 A complex combination of hydrocarbons obtained from prehydrogenated cracked naphtha after distillative separation of benzene- and toluene-containing hydrocarbon cuts and a higher boiling fraction. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C4 through C11 and boiling in the range of approximately 30°C to 205°C (86°F to 401°F).
Endpoint summary
Administrative data
Description of key information
Additional information
Acute Fish Toxicity:
Water accommodated fractions of isomerization naphtha produced a 96-hour LL50 value of 10 mg/L with Oncorhynchus mykiss. Water accommodated fractions of light alkylate naphtha produced a 96-hour LL50 value of 8.2 mg/L with Pimephales promelas. These data are used as read-across to all substances in the naphtha category.
Chronic Fish Toxicity:
Read across has been applied for this endpoint, using the results of long-term toxicity testing on invertebrates (Daphnia). Toxic effects of hydrocarbons are primarily caused by narcosis, and occur in a narrow range of molar concentrations across aquatic taxa; hence, read across between species is justified.
Acute Invertebrate Toxicity:
Water accommodated fractions of light straight-run naphtha produced a 48-hour EL50 value of 4.5 mg/L with Daphnia magna. These data are used as read-across to all substances in the naphtha category.
Chronic Invertebrate Toxicity:
Water accommodated fractions of light alkylate naphtha produced a 21 -day NOELR (No Observed Effect Loading Rate) value of 2.6 mg/L with Daphnia magna. These data are used as read-across to all substances in the naphtha category.
Algal Toxicity:
Water accommodated fractionsof gasoline produced a freshwater 72 -hour EL50 for Selenastrum capricornutum (new name: Pseudokirchnerella subcapitata) of 3.1 mg/L based on growth rate. The 72 -hour NOELR (No Observed Effect Loading Rate) value for Pseudokirchnerella subcapitata is 0.5 mg/L based on growth rate. These data are used as read-across to all substances in the naphtha category.
Microorganism Toxicity:
The estimated 72-hr LL50 value for Tetrahymena pyriformis, one of the most sensitive aquatic microorganism species, is 15.41 mg/L.
Some information for this category has been generated using the models PETROTOX and/or SPARC. The QMRFs for PETROTOX and SPARC are attached in IUCLID Section 13, with the associated QPRF.
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