Registration Dossier
Registration Dossier
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EC number: 203-765-0 | CAS number: 110-41-8
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.66 µg/L
- Assessment factor:
- 50
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 1.8 µg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 66 ng/L
- Assessment factor:
- 500
- Extrapolation method:
- assessment factor
- PNEC marine water (intermittent releases):
- 0.18 µg/L
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 10 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.265 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 26.5 µg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 52.6 µg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- PNEC oral
- PNEC value:
- 116 mg/kg food
- Assessment factor:
- 90
Additional information
Conclusion on classification
In accordance with Regulation EC 1272/2008, the substance requires classification as Aquatic Acute 1 (H400: Very toxic to aquatic life) on the basis of the LC/EC50 values being <= 1mg/L (96h LC50 for fish = 0.35mg/L; 48h EC50 for daphnia = 0.21mg/L; 72h ErC50 for algae inhibition = 0.18mg/L).
Chronic aquatic toxicity data is only available for two trophic levels (algae NOEC = 0.088mg/L and daphnia NOEC = 0.033mg/L). Therefore, the long-term hazard has been assessed based on both the available chronic data (a) and acute fish & environmental data (b):
a) The lowest chronic aquatic toxicity data is for daphnia (NOEC = 0.033 mg/L), which for a rapidly degradable substance results in a Chronic 2 classification
b) The 96h LC50 for fish is 0.35mg/L, the log Kow 4.9 and the substance readily biodegradable, which results in a Chronic 1 classification
Based on the most stringent outcome, it is concluded that the substance is classified Aquatic Chronic 1 (H410) according to the CLP Regulation 1272/2008/EC & adaptation 286/2011/EC.
In accordance with Table 4.1.3 of the regulation & adaptation 286/2011/EC in order to classify a mixture containing the substance, an M-factor of 1 should be used when applying the summation method. This applies to both the Acute 1 and Chronic 1 classification.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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