Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 253-256-2 | CAS number: 36888-99-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
- Endpoint:
- bioaccumulation in aquatic species: fish
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: Guideline study, a solubiliser was used
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 305 C (Bioaccumulation: Test for the Degree of Bioconcentration in Fish)
- GLP compliance:
- no
- Vehicle:
- yes
- Details on preparation of test solutions, spiked fish food or sediment:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Method: a stock solution was prepared by mixing 9.2 % test substance with about 20 % HC0 40 and about 70% water.
- Chemical name of vehicle (organic solvent, emulsifier or dispersant): Hardened castor oil = HCO 40 - Test organisms (species):
- Cyprinus carpio
- Details on test organisms:
- TEST ORGANISM
- Common name: common carp
- Source: bred at testing facility. Teichwirtschaftlicher Beispielbetrieb der Bezirksregierung Oberpfalz, Wöllershof, Germany
- Weight at study initiation (mean): 36.3 g
ACCLIMATION
- Type and amount of food: Fukosaim Anschlussfutter 2, Fuko-Kraftfutterfabrik, Ulm, Germany - Route of exposure:
- aqueous
- Test type:
- flow-through
- Water / sediment media type:
- natural water: freshwater
- Total exposure / uptake duration:
- 8 wk
- Test temperature:
- 25 ± 2 °C
- Dissolved oxygen:
- 6.8 - 8.3 mg/l
- Details on test conditions:
- TEST SYSTEM
- Test vessel: Giass vessel (130 l)
- Fill volume: 100 l
- Renewal rate of test solution (frequency/flow rate): 30 l/h per vessel; 720 l per day
- No. of organisms per vessel: 20
- No. of vessels per concentration (replicates): 1
- No. of vessels per control / vehicle control (replicates): 1
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: tap water - Nominal and measured concentrations:
- Nominal test substance concentrations:
1 mg/l and 0.1 mg/l
Analytically determined test concentrations [ppm]:
Nominal 1 mg/l: 0.966 (week 2), 0.987 (week 4), 0.966 (week 6), 0.956 (week 8)
Nominal 0.1 mg/l: 0.075 (week 2), 0.076 (week 4), 0.074 (week 6), 0.071 (week 8) - Type:
- BCF
- Value:
- 6.3
- Remarks on result:
- other: mean of two concentration factors measured after 8 weeks of exposure
- Remarks:
- Conc.in environment / dose:1 mg/l
- Type:
- BCF
- Value:
- 10.8
- Remarks on result:
- other: mean of two concentration factors measured after 8 weeks of exposure
- Remarks:
- Conc.in environment / dose:0.1 mg/l
- Details on results:
- The acute toxicity was tested in a 48-hour TLm50 study conducted with Oryzias latipes: > 920 and < 1 380 mg active ingredient -dye/l.
No mortality in the bioaccumulation test observed. - Endpoint:
- bioaccumulation in aquatic species: fish
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Reason / purpose for cross-reference:
- data waiving: supporting information
Referenceopen allclose all
Concentration factors in fish.
Nominal test substance concentration | fish | 2 weeks | 4 weeks | 6 weeks | 8 weeks |
1 mg/l | a | negative | 4.14 | 1.7 | 10.15 |
b | 0.42 | 2.24 | 3.41 | 2.44 | |
0.1 mg/l | a | 11.40 | 20.00 | 21.90 | 1.20 |
b | 19.20 | negative | 0.03 | 20.40 |
Description of key information
Accumulation in organisms is not to be expected.
Key value for chemical safety assessment
Additional information
Accumulation in organisms is not to be expected.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
