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Diss Factsheets

Administrative data

Endpoint:
nanomaterial aspect ratio/shape
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2022
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods with acceptable restrictions

Data source

Reference
Reference Type:
other: unpublished study report
Title:
Unnamed
Year:
2022
Report date:
2022

Materials and methods

Principles of method if other than guideline:
Method selection according to Gaillard et al., Nanoscale Adv., 2019, 1, 781
GLP compliance:
no
Type of method:
transmission electron microscopy
Details on methods and data evaluation:
TEM image evaluation according to Verleysen et al., Materials 2019, 12, 2274; doi:10.3390/ma12142274


Sample preparation: Dispersion in ethanol; transfer to carbon-coated TEM-grids.

Test material

Constituent 1
Chemical structure
Reference substance name:
5,5'-(1H-isoindole-1,3(2H)-diylidene)dibarbituric acid
EC Number:
253-256-2
EC Name:
5,5'-(1H-isoindole-1,3(2H)-diylidene)dibarbituric acid
Cas Number:
36888-99-0
Molecular formula:
C16H9N5O6
IUPAC Name:
5,5'-(1H-isoindole-1,3(2H)-diylidene)dipyrimidine-2,4,6(1H,3H,5H)-trione
Test material form:
solid: nanoform, no surface treatment
Details on test material:
Name of test substance: Pigment Yellow 139
Expiry date: 20 Jul 2030
Chemical name: 5,5'-(1H-isoindole-1,3(2H)-diylidene)dibarbituric acid
Physical state/appearance: Solid/orange
Storage conditions: Room temperature
Batch 200012P040

TEM: D50 = 55.8 nm (D10 = 24.6 and D90 = 195.2)
Aspect ratio: 1.9 : 1
shape: spherical
TEM: 19m2/g
Supplier: Sun Chemical Colors & Effects GmbH

Data gathering

Instruments:
TEM: Thermo-Fisher Osiris 200 kV

Results and discussion

Shape description
Key result
Shape:
spherical
Remarks on result:
other: The material is assigned to the “spheroidal” shape category
Aspect ratio
Key result
x Dimension:
1.9
y Dimension:
1
Remarks on result:
other: median (D50)

Any other information on results incl. tables

The number-based concentration of particles with sizes below 100 nm (smallest feret diameter) is ~62%. The median (D50) of the particle size is 55.8 nm.


The material is therefore classified as “nano” according to the definition of nanomaterial 2011/696/EU.

Applicant's summary and conclusion

Conclusions:
The particles have a median aspect ratio of 1.9:1.
The shape is “spherical”.The material is assigned to the “spheroidal” shape category.

The number-based concentration of particles with sizes below 100 nm (smallest feret diameter) is ~62%. The median (D50) of the particle size is 55.8 nm.
The material is therefore classified as “nano” according to the definition of nanomaterial 2011/696/EU.