Registration Dossier

Administrative data

Description of key information

Conclusions for Decanoic acid, mixed esters with dipentaerythritol, octanoic acid and valeric acid (EC# 270-470-1)are based on read-across from analogue substances of a known category.  In view of the structural similarities and similar physicochemical properties of the substance of interest with the other substances in the category, acute oral and acute dermal toxicity can be read-across: LD50 > 2000 mg/kg bw.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
2 000 mg/kg bw

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
Value:
2 000 mg/kg bw

Additional information

Conclusions for Decanoic acid, mixed esters with dipentaerythritol, octanoic acid and valeric acid (EC# 270-470-1)are based on read-across from analogue substances of a known category.

 

Data for acute oral toxicity are available for all members of the category except the substance of interest, i.e. Decanoic acid, mixed esters with dipentaerythritol, octanoic acid and valeric acid (EC# 270-470-1).

 

At a dose level of 2000 mg/kg bw, no mortalities were observed for any of the substances. Similar for acute dermal toxicity, no mortalities occurred at 2000 mg/kg bw and all LD50s are above 2000 mg/kg bw . In view of the structural similarities and similar physicochemical properties of the substance of interest with the other substances in the category, acute oral and acute dermal toxicity can be read-across: LD50 > 2000 mg/kg bw.

EC #

451-070-8

451-120-9

230-743-8

453-470-8

452-270-8

453-480-2

444-000-2

270-470-1

CAS #

70693-33-3

156559-00-1

7299-99-2

70851-05-7

-

70851-04-6

70693-38-8

68441-66-7

Avg MW

525

537

640

783

883

1012

1023

833

Acute oral LD50 [mg/kg]

> 2000

> 2000

> 2000

>2000

>2000

>2000

>2000

read-across: > 2000

Acute dermal LD50 [mg/kg]

> 2000

> 2000

read-across

read-across

read-across

read-across

>2000

read-across: > 2000

Avg MW = Average molecular weight

Justification for classification or non-classification

Based on the above mentioned result, classification according to the CLP Regulation (EC) 1272/2008 and the Dangerous Substance Directive 67/548/EC is not necessary.