Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 430-970-4 | CAS number: -
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Version / remarks:
- December 1992
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Version / remarks:
- March 1989
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7570 (Partition Coefficient, n-octanol / H2O, Estimation by Liquid Chromatography)
- Version / remarks:
- August 1996
- Deviations:
- no
- Principles of method if other than guideline:
- NA
- GLP compliance:
- no
- Type of method:
- calculation method (fragments)
- Remarks:
- calculation (Leo-Hansch method)
- Partition coefficient type:
- octanol-water
- Analytical method:
- other: theoretical calculation
- Key result
- Type:
- log Pow
- Partition coefficient:
- > 5
- Temp.:
- 20 °C
- Remarks on result:
- other: calculation
- Conclusions:
- The partition coefficient of the test substance was estimated to be log Pow > 5 using the Leo-Hansch method.
- Executive summary:
The partition coefficient of the test substance was estimated according to EU method A.8 (Leo-Hansch method), OECD Guideline 117, and EPA OPPTS 830.7570 guideline. The partition coefficient of the test substance was estimated to be log Pow > 5 using the Leo-Hansch method. The test substance was not soluble in n-octanol and only slightly soluble in water. Therefore, due to the low solubility of the test substance in water and n-octanol and the low sensitivity of the analytical methods available the experimental determination of the partition coefficient by any analytical technique was technically not feasible.
Reference
As the test substance consists of several constituents, for each constituent a partition coefficient was calculated. The partition coefficients (log Pow values) of all possible constituents are between 5.1 and 19.
Description of key information
The partition coefficient of the test substance was estimated to be log Pow > 5 using the Leo-Hansch method.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 5
- at the temperature of:
- 20 °C
Additional information
The partition coefficient of the test substance was estimated according to EU method A.8 (Leo-Hansch method), OECD Guideline 117, and EPA OPPTS 830.7570 guideline. The partition coefficient of the test substance was estimated to be log Pow > 5 using the Leo-Hansch method. The test substance was not soluble in n-octanol and only slightly soluble in water. Therefore, due to the low solubility of the test substance in water and n-octanol and the low sensitivity of the analytical methods available the experimental determination of the partition coefficient by any analytical technique was technically not feasible.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
