Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Dermal treatment of 3 rabbits on intact skin did not cause any adverse effects.
Ocular treatment of 3 rabbits caused no significant irritation with a maximum erythema grade 2 after 1 hour and no further findings .

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

The test material was non irritant on the intact skin of rabbits after treatment for 24 hours.

On the eyes of rabbits Naphtol AS D caused slight irritation of the conjunctivae with a maximum effect at 1 hour after application.

Justification for classification or non-classification

No effects observed for skin irritation

Minimal effects observed for eye irritation