2-chlorobenzaldehyde

Toxicity to terrestrial plants

Administrative data

Endpoint:

toxicity to terrestrial plants: short-term

Type of information:

experimental study

Adequacy of study:

other information

Reliability:

3 (not reliable)

Rationale for reliability incl. deficiencies:

other: No information on purity of substance, no information on replicates and no information on statististcal evalutation is given, results are described inaccurately.

Data source

Reference

Reference Type:

publication

Title:

The Relationship Between the Constitution and the Effect of Chemical Compounds on Plant Growth - 3. Chlorinated Benzaldehydes and Benzoic Acids

Author:

Jones, R. et al.

Year:

1951

Bibliographic source:

Biochem. J. 48:422-425

Materials and methods

Test guideline

Qualifier:

no guideline followed

Principles of method if other than guideline:

Rape and wheat seeds germinating on agar are used as indicator of toxicity in that their root length reduction is measured in comparison to control seedlings.

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

2-chlorobenzaldehyde

EC Number:

201-956-3

EC Name:

2-chlorobenzaldehyde

Cas Number:

89-98-5

Molecular formula:

C7H5ClO

IUPAC Name:

2-chlorobenzaldehyde

Sampling and analysis

Analytical monitoring:

not specified

Test substrate

Vehicle:

not specified

Test organisms

1

Species:

Brassica napus

Plant group:

Dicotyledonae (dicots)

2

Species:

Triticum aestivum

Plant group:

Monocotyledonae (monocots)

Study design

Test type:

seed germination/root elongation toxicity test

Study type:

laboratory study

Substrate type:

other: agar

Limit test:

no

Results and discussion

Effect concentrations

Effect concentrations 1

Species:

Brassica napus

Dose descriptor:

other: >= 20% root length reduction in > 50% of seedlings

Effect conc.:

1 mg/kg soil dw

Nominal / measured:

not specified

Conc. based on:

not specified

Effect concentrations 2

Species:

Brassica napus

Dose descriptor:

other: >= 20% root length reduction in > 50% of seedlings

Effect conc.:

10 mg/kg soil dw

Nominal / measured:

not specified

Conc. based on:

not specified

Effect concentrations 3

Species:

Brassica napus

Dose descriptor:

other: >= 50% root length reduction in > 50% of seedlings

Effect conc.:

50 mg/kg soil dw

Nominal / measured:

not specified

Conc. based on:

not specified

Effect concentrations 4

Species:

Triticum aestivum

Dose descriptor:

other: >= 20% root length reduction in > 50% of seedlings

Effect conc.:

10 mg/kg soil dw

Nominal / measured:

not specified

Conc. based on:

not specified

Effect concentrations 5

Species:

Triticum aestivum

Dose descriptor:

other: >= 20% root length reduction in > 50% of seedlings

Effect conc.:

50 mg/kg soil dw

Nominal / measured:

not specified

Conc. based on:

not specified

Applicant's summary and conclusion

Conclusions:

In this pre-guideline study from 1951, a value similar to an EC50 had been determined for 2-chlorobenzaldhyde in regard to the dicot rape (Brassica napus): 50 mg/kg [>= 50'% reduction in root length in > 50% of the seedlings) and a value similar to an EC20 in regard to the monocot wheat (Triticum aestivum): 10-50 mg/kg (>= 20'% reduction in root length in > 50% of the seedlings).
Toxicity of 2-chlorobenzaldhyde therefore may be more pronounced to dicots than to monocts.

Executive summary:

In this publication, the toxicity of 2-chlorobenzaldehyde to seedlings of the monocot wheat (Triticum aestivum) and the dicot rape (Brassica napus) is examined by the means of determination of growth reduction of the roots on agar as a substitute for soil. Root length had been compared to untreated seedlings on agar. No information on statistics is given, and results are given schematically in relation to a "larger or equal to" effect on root length in regard to more than 50% of the seedlings. A relation to EC25 or EC50 is therefore difficult.