Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 202-547-2 | CAS number: 96-96-8
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- RTECS Number: BY4415000
- Year:
- 2 012
- Bibliographic source:
- RTECS (Registry of Toxic Effects of Chemical Substances):- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,718,1986
- Reference Type:
- other: Authoritative data base
- Title:
- No information
- Author:
- IFA (GESTIS)
- Year:
- 2 011
- Bibliographic source:
- GESTIS - Substance Database (Information system on hazardous substances of the Berufsgenossenschaften)
- Reference Type:
- review article or handbook
- Title:
- DPIM: MFB000
- Author:
- Richard J. Lewis, Sr.
- Year:
- 2 007
- Bibliographic source:
- SAX (Sax's Handbook of Dangerous Industrial Materials):- 85JCAE Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J., Prague, Czechoslovakia.: , Avicenum, 1986, 718.
- Reference Type:
- review article or handbook
- Title:
- M143
- Author:
- RSC Publishing
- Year:
- 2 011
- Bibliographic source:
- Dictionary of Substances and their effects (DOSE):- Marhold, J. V. Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku 1972, Prague, Czechoslovakia.
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- standard acute method
- GLP compliance:
- not specified
- Test type:
- standard acute method
Test material
- Reference substance name:
- 2-nitro-p-anisidine
- EC Number:
- 202-547-2
- EC Name:
- 2-nitro-p-anisidine
- Cas Number:
- 96-96-8
- Molecular formula:
- C7H8N2O3
- IUPAC Name:
- 4-methoxy-2-nitroaniline
Constituent 1
Test animals
- Species:
- rat
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- unchanged (no vehicle)
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 14 100 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: Details of toxic effects not reported other than lethal dose value
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The LD50 value of the substance is found to be 14100 mg/kg in rats by oral route.
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