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Environmental fate & pathways

Hydrolysis

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Description of key information

Homosalate has been investigated for abiotic hydrolysis at  pH 4, pH 7 and pH 9 and showed to be rapidly degraded under environmentally relevant pH with a estimated half-life of 215 hours at neutral pH (pH 7).

Key value for chemical safety assessment

Half-life for hydrolysis:
215 h
at the temperature of:
25 °C

Additional information

The assessment of hydrolytic stability of the test compound was carried out using a procedure designed to be compatible with Method C7 Abiotic Degradation, Hydrolysis as a Function of pH of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 111 of the OECD Guidelines for Testing of Chemicals, 13 April 2004. The results are as follows:

pH 4 Estimated half-life at 25 °C is 210 hours

pH 7 Estimated half-life at 25 °C is 215 hours

pH 9 Estimated half-life at 25 °C is 69.7 hours

With a half-life time of < 16 days (9 days for pH 7) the criteria for rapid degradation according to the CLP/GHS criteria are fulfilled as the degradation products salicylic acid (2-hydroxylbenzoic acid) and 3,3,5-trimethylcyclohexanol are not classified as hazardous to the aquatic environment.