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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
QSAR prediction

Data source

Reference
Reference Type:
publication
Title:
BUA-Stoffbericht 265 - 2-Chlorbezonitril, 4-Chlorbenzonitril
Author:
n.a.
Year:
2006
Bibliographic source:
Beratergremium für Altstoffe (BUA) der Gesellschaft Deutscher Chemiker, S.Hirzel Wissenschaftliche Verlagsgesellschaft

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
QSAR; calculation on basis of log Kow using EPISUITE 3.12 (US-EPA 2004)
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-chlorobenzonitrile
EC Number:
212-836-5
EC Name:
2-chlorobenzonitrile
Cas Number:
873-32-5
Molecular formula:
C7H4ClN
IUPAC Name:
2-chlorobenzonitrile
impurity 1
Reference substance name:
unknown
IUPAC Name:
unknown
Test material form:
solid

Test organisms

Test organisms (species):
Daphnia sp.

Results and discussion

Effect concentrations
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
72 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.

Applicant's summary and conclusion

Validity criteria fulfilled:
not applicable
Conclusions:
The calculated 48-h EC50 of 2-chlorobenzonitrile for Daphnia using EPISUITE 3.12 (US-EPA 2004) is 72 mg/L.
Executive summary:

As no experimental data are available the 48-h EC50 of 2-chlorobenzonitrile for Daphnia was calculated using EPISUITE 3.12 (US-EPA 2004). The calculated 48-h EC50 is 72 mg/L.