Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
publication
Title:
BUA-Stoffbericht 265 - 2-Chlorbezonitril, 4-Chlorbenzonitril
Author:
n.a.
Year:
2006
Bibliographic source:
Beratergremium für Altstoffe (BUA) der Gesellschaft Deutscher Chemiker, S.Hirzel Wissenschaftliche Verlagsgesellschaft

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Hydrolysis of 2-chlorobenzonitrile was followed by incubation of 0.14 mg/L = 1 µmol/L test substance in sediment samples of an eutrophic pond situated in the Netherlands at 22 °C and pH = 7.3. Hydrolysis was terminated by addition of acetonitrile.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
2-chlorobenzonitrile
EC Number:
212-836-5
EC Name:
2-chlorobenzonitrile
Cas Number:
873-32-5
Molecular formula:
C7H4ClN
IUPAC Name:
2-chlorobenzonitrile
impurity 1
Reference substance name:
unknown
IUPAC Name:
unknown
Test material form:
solid
Radiolabelling:
no

Study design

Analytical monitoring:
not specified
Positive controls:
not specified
Negative controls:
not specified

Results and discussion

Transformation products:
not specified
Dissipation DT50 of parent compound
Key result
pH:
7.3
Temp.:
22 °C
DT50:
160 d
Type:
not specified

Applicant's summary and conclusion

Validity criteria fulfilled:
not applicable
Conclusions:
The hydrolysis half-life for 2-chlorobenzonitrile was determined to be 160 +/- 40 d, but biologiocal degradation cannot be excluded.
Executive summary:

Hydrolysis of 2-chlorobenzonitrile was followed by incubation of 0.14 mg/L = 1 µmol/L test substance in sediment samples of an eutrophic pond situated in the Netherlands at 22 °C and pH = 7.3. Hydrolysis was terminated by addition of acetonitrile.

The hydrolysis half-life was determined to be 160 +/- 40 d.

In control experiments in pure water with various nitriles the test substances were not hydrolyzed. Therefore, biological degradation processes cannot totally be excluded.