Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
repeated dose toxicity: other route
Adequacy of study:
other information
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: No further information. No details of sex, strains, group sizes or period of administration.

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
Unnamed
Year:
1994
Reference Type:
publication
Title:
Toxicity of methylolmethacrylamide.
Author:
Novikov SM, Porokhova LA, Kozeeva EE
Year:
1988
Bibliographic source:
Gig. Tr. Prof. Zabol. 9: 55 - 56

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
N-(hydroxymethyl)methacrylamide
EC Number:
213-086-1
EC Name:
N-(hydroxymethyl)methacrylamide
Cas Number:
923-02-4
Molecular formula:
C5H9NO2
IUPAC Name:
N-(hydroxymethyl)-2-methylacrylamide

Test animals

Species:
rat

Results and discussion

Target system / organ toxicity

Critical effects observed:
not specified

Any other information on results incl. tables

Results:
On repeated exposure to N-Methylolmethacrylamide, rats developed ataxia.

Applicant's summary and conclusion