Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

An oral and an inhalation absorption is predicted from the phys.-chem. properties. An oral absorption was observed in the acute oral toxicity studies.
The dermal absorption is predicted to be lower.
A distribution was detected in the acute oral toxicity studies.
Diacetone acrylamide can be metabolised in vitro by hepatic microsomal enzymes and by a glutathione conjugation reaction to not identified molecules.
No accumulation is expected, based on the low log Pow.
No relevant data are available, which provide evidence on the route of excretion.

Key value for chemical safety assessment

Bioaccumulation potential:
no bioaccumulation potential

Additional information