Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Short-term toxicity:


Diacetone acrylamide was tested for acute fish toxicity, using equivalent methods to OECD and EC methods, in a semistatic test with 48 h exposure duration. The LC50 was 1960 mg/L, the NOEC was 1000 mg/L.


The 48-hour EC50 for diacetone acrylamide to Daphnia was >100 mg/L. The NOEC was 100 mg/L.


The EC50,72h of diacetone acrylamide to algae was >100 mg/L and the NOEC was 100 mg/L.


The EC50,3h of diacetone acrylamide to activated sludge was >1000 mg/L and the NOEC was 1000 mg/L.

Long-term toxicity:

Long-term tests are waived because no classification and no risk assessment has to be performed.