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EC number: 240-004-1 | CAS number: 15875-13-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
The material has a low log Kow in the range of 0.26 to 0.18 so bioaccumulation is not expected. Tests in multiple species demonstrate minimal or no systemic toxicity. Primarily local effects (irritation of the skin, stomach, and mucous membranes) were seen. This suggests that absorbtion into the body is minimal.
Key value for chemical safety assessment
- Bioaccumulation potential:
- low bioaccumulation potential
Additional information
The material has a low log Kow in the range of 0.26 to 0.18 so bioaccumulation is not expected. Tests in multiple species demonstrate minimal or no systemic toxicity. Primarily local effects (irritation of the skin, stomach, and mucous membranes) were seen. This suggests that absorbtion into the body is minimal.
Dermal absorption of low molecular weight (< 500 Daltons) substances with log Pow between -1 and 4 is anticipated. These compounds are also expected to be well absorbed in the respiratory and gastro-intestinal tracts.
The water solubility of the substance favors extensive and even systemic distribution via the circulatory system.
There is a commonality in the metabolism of the tertiary amines. N-oxide formation and excretion of both freebase and N-oxide forms, with some dealkylation, appears to be the major route of excretion for the lower molecular weight tertiary amines.
QSAR indicates extensive metabolism; the production of a number of highly water-soluble metabolites favors urinary excretion and indicates that bioaccumulation is unlikely.
Since the physical-chemical properties of this material favor absorption and the material is relatively non-toxic to aquatic and mammalian organisms, it is believed that this material is rapidly detoxified and or excreted unchanged from the body.
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