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Physical & Chemical properties

pH

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Administrative data

Endpoint:
pH
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report date:
2012

Materials and methods

Principles of method if other than guideline:
pH-measurements (10g/l) taken in the laboratory for solutions of pure, cyclic HEBMP-H with increasing stoichometric amounts of the corresponding base (NaOH).
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
[(2-hydroxy-2-oxo-1,4,2-oxazaphosphinan-4-yl)methyl]phosphonic acid
Cas Number:
32422-02-9
Molecular formula:
C4H11NO6P2
IUPAC Name:
[(2-hydroxy-2-oxo-1,4,2-oxazaphosphinan-4-yl)methyl]phosphonic acid

Results and discussion

pH valueopen allclose all
pH value:
2.8
Temp.:
20 °C
Concentration:
10 g/L
Remarks on result:
other: Stoichiometric loading of base equivalent to cyclic HEBMP
pH value:
4.1
Temp.:
20 °C
Concentration:
10 g/L
Remarks on result:
other: Stoichiometric loading of base equivalent to cyclic HEBMP-1
pH value:
6.7
Temp.:
20 °C
Concentration:
10 g/L
Remarks on result:
other: Stoichiometric loading of base equivalent to cyclic HEBMP-2
pH value:
10
Temp.:
20 °C
Concentration:
10 g/L
Remarks on result:
other: Stoichiometric loading of base equivalent to HEBMP-3

Any other information on results incl. tables

Table 1: Titration in water

Determination 1

Sample mass (1) cyc-HEBMP (mg) 69.71

Equivalent NaOH

0

1

2

3

1N NaOH (ml)

0.000

0.301

0.602

0.903

pH

2.74

4.34

7.26

10.31

Determination 2

Sample mass (1) cyc-HEBMP (mg) 69.71

Equivalent NaOH

0

1

2

3

1N NaOH (ml)

0.000

0.301

0.602

0.903

pH

2.73

4.20

7.05

10.16

Average

2.74

4.27

7.16

10.24

 

Table 2: Titration in 0.2 M KCl

Determination 1

Sample mass (1) cyc-HEBMP (mg) 69.71

Equivalent NaOH

0

1

2

3

1N NaOH (ml)

0.000

0.301

0.602

0.903

pH

2.78

4.00

6.56

9.84

Determination 2

Sample mass (1) cyc-HEBMP (mg) 69.71

Equivalent NaOH

0

1

2

3

1N NaOH (ml)

0.000

0.301

0.602

0.903

pH

2.80

4.10

6.77

10.16

Average

2.79

4.05

6.67

10.00

Applicant's summary and conclusion

Conclusions:
The pH of cyclic-HEBMP has been determined using an acceptable scientific method. The result is considered reliable.