Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Direct observations: clinical cases, poisoning incidents and other

Currently viewing:

Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
experimental study
Adequacy of study:
other information
Study period:
1999
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Method not validated

Data source

Reference
Reference Type:
publication
Title:
Variation in volatile organic compounds in the breath of normal humans
Author:
Phillips et al.
Year:
1999
Bibliographic source:
Journal of chromatography B, 729 (1999) 75-88

Materials and methods

Study type:
study with volunteers
Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Benzothiazole was analysed in the breath of 50 volunteers, using gas chromatography and mass spectroscopy.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzothiazole
EC Number:
202-396-2
EC Name:
Benzothiazole
Cas Number:
95-16-9
Molecular formula:
C7H5NS
IUPAC Name:
benzothiazole
Details on test material:
- Name of test material (as cited in study report): benzothiazole
- Analytical purity: no data

Method

Reason of exposure:
other: analytical study of volatile organic compounds in the breath of normal humans
Exposure assessment:
measured

Results and discussion

Any other information on results incl. tables

Study of variation in volatile organic compounds (VOCs) in the breath of 50 normal humans, using gas chromatography and mass spectroscopy. A mean alveolar gradient of 0.93 in 98 % of analysed subject was observed.

Applicant's summary and conclusion