Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

No studies on short-term terrestrial toxicity are available for this substance. Read-across to the ecotoxicological properties of Hexanoic acid, 3,5,5-trimethyl-, 1,1'-[2-ethyl-2-[[(3,5,5-trimethyl-1-oxohexyl)oxy]methyl]-1,3-propanediyl] ester (EC 613-848-7, CAS65870-94-2),fatty acid polyols (Fatty acids, C5-9, esters with pentaerythritol (EC 270-290-3, CAS 68424-30-6) and Decanoic acid, ester with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol octanoate (EC 234-392-1, CAS 11138-60-6)) and their analogues is applicable based on the similarity in structure and physico-chemical properties. The substance with the CAS No. 68002 -79 -9 is a structural analogue of the read-across substances and can therefore be used for read-across.

 

Due to the high Koc a considerable adsorption to sediment and soil is indicated. However, EC 613 -848 -7 has been shown to be readily biodegradable. Therefore, no chronic exposure of terrestrial organisms is expected. Furthermore, the abstract of a terrestrial plant toxicity test (short-term, OECD 208, Kirch 1996) performed on the read-across substance Fatty acids, C14-18 and C16-18 unsatd., triesters with trimethylolpropane (CAS 68002-79-9) indicates no toxicity (NOEC = 300-1000 mg/kg soil dw, LOECs = 1000 mg/kg soil dw). In addition, Fatty acid esters are metabolised into fatty acids and alcohols. These components occur in sediment and soils naturally, are part of physiological pathways and can be used as energy source. The enzyme carboxylesterase is omnipresent in the environment, readily degrading this test substance. Thus, toxic effects caused by the metabolites of fatty acid esters are implausible.

 

In conclusion, due to a) the observed absence of toxicological effects on aquatic organisms (assumption that soil toxicity expressed in terms of the freely-dissolved substance concentration in the pore water is the same as aquatic toxicity, ECHA Guidance on Information Requirements Chapter R.10), b) the lack of chronic exposure and c) the, acknowledged metabolisation of fatty acid esters, toxic effects to terrestrial organisms can be excluded.

Additional information