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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)
Deviations:
no
Remarks:
The study was conducted according to the test guidelines in effect at the time of study conduct.
GLP compliance:
yes
Type of method:
electrical sensing zone (e.g. Coulter) method
Type of distribution:
volumetric distribution
Percentile:
D50
Mean:
ca. 95 µm
Remarks on result:
other: st. dev. not reorted
Percentile:
other: percentage less than 10 um
Mean:
ca. 1 µm
Remarks on result:
other: st. dev. not reported
No.:
#1
Size:
<= 2.039 µm
Distribution:
0.05 %
No.:
#2
Size:
<= 10.2 µm
Distribution:
1.04 %
No.:
#3
Size:
>= 199.3 µm
Distribution:
8.66 %
No.:
#4
Size:
>= 2.039 - <= 199.3 µm
Distribution:
91.29 %
Conclusions:
The particle size distribution of the test substance was between 0.739 and 419.0 µm equivalent spherical diameter.
Executive summary:

This study was designed to determine the particle size distribution of the test substance in accordance with OECD Guideline 110. The particle size distribution was between 0.739 and 419.0 µm equivalent spherical diameter, with 0.05% by volume less than or equal to 2.039 µm, 8.66% greater than or equal to 199.3 µm, and 91.29% between 2.039 and 199.3 µm. Assuming a normal distribution, spherical particles, and unit density, the calculated mass median aerodynamic diameter would be approximately 95 µm, and the calculated percentage less than 10 µm aerodynamic diameter would be approximately 1%.

Description of key information

OECD Guideline 110

Additional information

1% are 10 µm or smaller, 90% are in the range of 11-199 µm, and 9% are larger than 200 µm; particle size range 0.739-419 µm