Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study was conducted according to EEC and O.E.C.D. Testing Guidelines with GLP compliance.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report Date:
2010

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
yes (incl. certificate)
Type of method:
flask method
Remarks:
with HPLC detection.

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Type:
Constituent
Details on test material:
As per IUCLID5 Sections 1.1. - 1.4.

Results and discussion

Water solubility
Water solubility:
2.3 g/L
Temp.:
20 °C
pH:
ca. 2.1
Details on results:
The detector calibration was found to be linear over the range 0 to 100 mg/l of standard solutions in mobile phase with a regression coefficient of 1.0000. The water solubility of Crude 1,3-dichloropropene was 2.26 ± 0.14 g/l. A mean recovery of approximately 85% of Crude 1,3-dichloropropene from fortified control samples was achieved and deemed to be acceptable.

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
Crude 1,3-dichloropropene was found to be slightly soluble in water at 2.26 ± 0.14 g/l at 20 degrees C.
Executive summary:

The water solubility of Crude 1,3 -Dichloropropene was determined according to EEC Method A6 and O.E.C.D. Testing Guideline 105 with HPLC detection and GLP compliance. Crude 1,3-dichloropropene was found to be slightly soluble in water at 2.26 ± 0.14 g/l at 20 degrees C.