Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study was conducted according to EEC Method A8 and O.E.C.D. Testing Guideline 117 Partition Coefficient with GLP compliance.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report Date:
2010

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method A.8 (Partition Coefficient)
GLP compliance:
yes (incl. certificate)
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Details on test material:
As per IUCLID5 Sections 1.1. - 1.4.

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
2.3
Temp.:
25 °C
Remarks on result:
other: pH unknown, standard conditions.
Details on results:
Crude 1,3-dichloropropene was found to have a log10Pow value of 2.3.

Applicant's summary and conclusion

Conclusions:
Crude 1,3-dichloropropene was found to have a log10Pow value of 2.3. This experimental Log Pow value is in agreement with the QSAR KOWWIN, Version 1.67, U.S. Environmental Protection Agency estimated value of 2.25. These data suggest that Crude 1,3-dichloropropene has little or no potential to bioconcentrate in the aquatic environment.
Executive summary:

The Partition Coefficient (Log Pow) of Crude 1,3 -Dichloropropene was determine experimentally by EEC Method A8 and O.E.C.D. Testing Guideline No. 117 (HPLC method) with GLP compliance and by QASR modeling (KOWWIN, Version 1.67, U.S. Environmental Protection Agency). Crude 1,3-dichloropropene was found to have a log10Pow value of 2.3. This experimental Log Pow value is in agreement with the QSAR KOWWIN, Version 1.67, U.S. Environmental Protection Agency estimated value of 2.25. These data suggest that Crude 1,3 -Dichloropropene has little or no potential to bioconcentrate in the aquatic environment.