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Diss Factsheets
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EC number: 225-306-3 | CAS number: 4767-03-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1999-3-12 - 1999-04-09
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 A (Ready Biodegradability: DOC Die Away Test)
- Deviations:
- no
- GLP compliance:
- yes
- Specific details on test material used for the study:
- - Name of the test material used in the study report: Dimethylolpropionsäure, 2,2-Bis(hydroxymethyl)propansäure
- Batch no.: SE 8069
- Purity: 99.4%
- Storage conditions: storage at room temperature - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- Activated sludge from laboratory waste water plants treating municipal and synthetic sewage. Concentration of the dry matter was 30 mg/L.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 42 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- TEST CONDITIONS
- Composition of medium: Activated sludge from laboratory waste water plants
- Additional substrate: None
- Solubilising agent (type and concentration if used): not required
- Test temperature: No data
- pH: No data
- pH adjusted: No data
- CEC (meq/100 g): No data
- Aeration of dilution water: No data
- Suspended solids concentration: 30 mg/L
- Continuous darkness: No data - Reference substance:
- aniline
- Preliminary study:
- No data available
- Test performance:
- No data available
- Parameter:
- % degradation (DOC removal)
- Value:
- 90 - 100
- Sampling time:
- 28 d
- Details on results:
- Over the ten day window from day 10 to day 20 DOC removal of the test substance increased from approximately 10% on day 10 to greater than 90% by day 20.
- Results with reference substance:
- DOC removal of the test substance (aniline) was rapid with greater than 90% removal being observed by day 5 of the study.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The substance is readily biodegradable.
- Executive summary:
In a study conducted to guideline OECD 301A, Bis-MPA was 90 -100% biodegradaded over 28 days (i.e. >70%). During the 10-day window removal of DOC increased from 10% to over 90%. The substance Bis-MPA is therefore readily biodegradable and biological removal in the environment can be considered to be complete and rapid.
Reference
After an initial period of equilibration DOC removal for the test substance was rapid and efficient. Over the ten day period between day ten and day twenty DOC removal moved from a mean of 10% to over 90%. This indicates the substance has reached the pass criterium for ready biodegradability and can be considered fully and readily biodegradable.
Description of key information
The substance Bis-MPA is readily biodegradable in a study conducted to OECD guideline 301A.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
A classification of readily biodegradable means that Bis-MPA will be rapidly and effectively removed from the environmental compartments by biological degradation. As such removal from the STP is expected to be highly efficient and half lives in soil and sediment will be short. Thus, the likelihood of long-term residence in the environment is considered to be negligible for Bis-MPA.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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