Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 287-370-9 | CAS number: 85480-89-3
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
No study of bioaccumulation conducted with EDTMP-xCaxNa is available. Given the very low estimated value of log Kow (-4), bioaccumulation is expected to be very low. A reliable study of bioaccumulation of DTPMP-xNa in carp, indicates a bioconcentration factor in the exposure phase of <10 (Concentration level 18.8mg/l) and <94 (concentration level 2.03 mg/l). No active uptake mechanisms (i.e. mediated by enzymes) can occur for phosphonates.
Key value for chemical safety assessment
- BCF (aquatic species):
- 94 dimensionless
Additional information
The registration substance is part of a category family (super-category; see CSR for more details) which consists of several phosphonates that share a common chemistry incorporating alkyl backbones with one or more tertiary amine centres and multiple methylphosphonate groups present.
EDTMP acid (CAS 1429-50-1) has two aminobismethylphosphonate groups, connected by an ethylidene chain. DTPMP acid (CAS 15827-60-8) has three amine centres (five methylphosphonate groups), connected by ethyl chains.
As well as being structural analogues, both phosphonates have consistent chemical properties including high MW (436 and 573 respectively), very low log Kow(≤-3 for both substances) and are highly soluble in water. The substances generally possess similar physico-chemical properties and are not readily biodegradable.
The sodium counterion of these phosphonates is not significant in respect of the properties under consideration and has been assessed in depth in the public literature. Additionally, the counterion is expected to dissociate when in contact with water, including atmospheric moisture.In view of the high levels of calcium ions typically present in natural waters and test media, the Ca2+ion is not expected to be significant.
Therefore, for the purpose of this assessment, read-across is considered valid.
Further information on the super-category and the validity of read-across are presented in the CSR Chapter 1.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
