Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Study period:
7.10.1991 - 19.11.1991
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: GLP guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1991
Report Date:
1991

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
Deviations:
yes
Remarks:
Due to the poor solubility of the test substance in water, an emulsifier was used to achieve a better distribution in the medium.
GLP compliance:
yes (incl. certificate)

Test material

Reference
Name:
Unnamed
Type:
Constituent

Study design

Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, domestic (adaptation not specified)
Duration of test (contact time):
28 d
Initial test substance concentrationopen allclose all
Initial conc.:
10 mg/L
Based on:
test mat.
Initial conc.:
20.2 mg/L
Based on:
test mat.
Parameter followed for biodegradation estimation
Parameter followed for biodegradation estimation:
CO2 evolution
Reference substance
Reference substance:
aniline

Results and discussion

% Degradationopen allclose all
Parameter:
% degradation (CO2 evolution)
Value:
4
Sampling time:
28 d
Remarks on result:
other: for 10 mg test substance/L
Parameter:
% degradation (CO2 evolution)
Value:
2
Sampling time:
28 d
Remarks on result:
other: for 20.2 mg test substance/L
Details on results:
Degradation kinetic:
Day 3: 0%
Day 10: 68%
Day 20: 80%
Day 28: 86%

Applicant's summary and conclusion

Interpretation of results:
under test conditions no biodegradation observed
Conclusions:
According the classification criteria described in REGULATION (EC) No 1272/2008 (CLP), the product is not readily biodegradable..