Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Acceptable, well documented company data which meets basic scientific principles

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
1996
Report Date:
1996

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
The Kow was determnied at different pH conditions.
GLP compliance:
no
Type of method:
other: measured
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
> 3.3
Temp.:
37 °C
pH:
7

Any other information on results incl. tables

n-Octanol / water: Kow > 2000 :1

n-Octanol / hydrochloride acid 0.1 N: Kow = 68:1

n-Octanol / aqueous buffer pH 4.0: Kow = 226:1

n-Octanol / aqueous buffer pH 7.0: Kow > 2000:1

n-Octanol / aqueous buffer pH 9.0: Kow > 2000:1

Applicant's summary and conclusion