Registration Dossier

Administrative data

Endpoint:
bioaccumulation: aquatic / sediment
Type of information:
other: OECD SIDS
Adequacy of study:
other information
Reliability:
other: OECD SIDS
Rationale for reliability incl. deficiencies:
other: no reliability is given as this is a summary entry for the OECD SIDS

Data source

Referenceopen allclose all

Reference Type:
secondary source
Title:
Phthalimide - CAS No: 85-41-6
Author:
OECD SIDS
Year:
2005
Bibliographic source:
SIDS Initial Assessment Report for 20th SIAM, UNEP Publications
Reference Type:
other company data
Title:
Unnamed
Year:
2004
Report Date:
2004
Reference Type:
publication
Title:
Unnamed
Year:
1993

Materials and methods

Principles of method if other than guideline:
OECD SIDS
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Any other information on results incl. tables

OECD SIDS (2005):

 

Bioconcentration factors (BCF) measured for fish (Cyprinus carpio) by a test procedure similar to the OECD TG 305C were in the range of 4.6-8.5 for 1.0 mg/l and 4.7-22 for 0.1 mg/l phthalimide, respectively (MITI, 1993).

Taking into account the octanol-water partition coefficient, a bioconcentration factor (BCF) can be calculated with the BCFWIN Program (v. 2.15). Using an experimental log Kowof 1.15, the calculated BCF was 1.53 (Bayer Industry Services, 2004).

Thus no significant potential for bioaccumulation of phthalimide in aquatic organisms is indicated.

 

Bioaccumulative properties of phthalimide in fish:

 

Organism

Method

BCF

Reference

Fish

Calculated with BCFWIN, v. 2.15

BCF = 1.53

BayerIndustry Services, 2004

Cyprinuscarpio

Comparable to OECD TG 305C

BCF = 4.6-8.5 at 1.0 mg/l
BCF = 4.7-22 at 0.1  mg/
after 42 d

MITI, 1993

 

 

 

 

Applicant's summary and conclusion