Registration Dossier
Registration Dossier
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EC number: 231-820-9 | CAS number: 7757-82-6
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Literature data
Data source
Reference
- Reference Type:
- publication
- Title:
- Pharmacological Studies on Alkylbenzenesulfonate.
- Author:
- Okahara Kunio, Kurayuki Yoshio, Iseki Motohachi, Taniguchi Shigeru and Yamada Akio
- Year:
- 1 963
- Bibliographic source:
- Food Hygiene Journal (Shokuhin Eiseigaku Zassi) 4:15.
Materials and methods
- Principles of method if other than guideline:
- Probit method.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Sodium sulphate
- EC Number:
- 231-820-9
- EC Name:
- Sodium sulphate
- Cas Number:
- 7757-82-6
- Molecular formula:
- H2O4S.2Na
- IUPAC Name:
- disodium sulfate
Constituent 1
Test animals
- Species:
- mouse
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- water
Results and discussion
Effect levelsopen allclose all
- Dose descriptor:
- LD50
- Effect level:
- ca. 6 346 mL/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: 24-h
- Dose descriptor:
- LD50
- Effect level:
- ca. 5 989 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: 7 days
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Criteria used for interpretation of results: EU
- Conclusions:
- LD50 at 7 days = 5989 mg/kg bw
- Executive summary:
LD50 at 7 days = 5989 mg/kg bw
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