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EC number: 221-486-2
CAS number: 3115-49-9
Two studies on the short-term toxicity to fish are available, the key
study (CIBA-GEIGY, 1985) with a warmwater fish (zebrafish) and the
supporting study (CIBA-GEIGY, 1978) with four coldwater fish (rainbow
trout, carp, catfish and bluegill).
The 96 hour acute toxicity to zebrafish (Danio rerio) was
assessed under static conditions. The calculated 96 hour LC50 based on
mortality was 9 mg/L. Therefore, the test item is acutely toxic to fish.
Daphnia magna were exposed to the test item for 48 hours under
static conditions (Institute of Industrial organic Chemistry Branch
Pszczyna, 2012). The 48 hour EC50 was determined to be 0.88 mg/L.
Therefore, the test item is acutely very toxic to aquatic invertebrates.
Cultures of Pseudokirchneriella subcapitata were exposed to the
test item under static conditions in accordance with the OECD guideline
201 (2006) (Institute of Industrial organic Chemistry Branch Pszczyna,
The inhibition of algae growth rate resulted in a ErC50 (72 h) of 27.21
mg/L, whereas the inhibition of algae yield resulted in a EyC50 (72 h)
of 18.37 mg/L. Therefore, the test item is acutely harmful to aquatic
Sewage sludge microorganisms were exposed to the test item (CIBA-GEIGY,
1989). The IC50 value based on respiration rate was ≥100 mg/L after a
3 h contact time. Therefore, the inhibition of the degradation activity
of activated sludge is not anticipated when introduced in appropriate
In general, it should be mentioned that the composition contains < 1 %
p-Nonylphenol (CAS 104-40-5) as impurity. p-Nonylphenol is part of the
branched and linear [substances with a linear and/or branched alkyl
chain with a carbon number of 9 covalently bound in position 4 to
phenol, covering also UVCB- and well-defined substances which include
any of the individual isomers or a combination thereof]" for
the Candidate List of Substances
of Very High Concern for Authorisation (Decision number ED/169/2012;
Equivalent level of concern having probable serious effects to the
environment (Article 57 f)).
However, no decision
is made by now.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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