Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Identified in ECHA review article, no reference given, full literature article unable to be located.
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Reference
Reference Type:
publication
Title:
Pharmacodynamie. - Sur la toxicite des acides phtaliques.
Author:
Caujolle M.F., Meynier D.
Year:
1958
Bibliographic source:
C. R. Academie des Sciences, 246, 851-852

Materials and methods

Principles of method if other than guideline:
Method not determined: reference not located
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzoic acid
EC Number:
200-618-2
EC Name:
Benzoic acid
Cas Number:
65-85-0
Molecular formula:
C7H6O2
IUPAC Name:
benzoic acid

Test animals

Species:
mouse

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
other: isotonic saline

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
1 460 mg/kg bw

Applicant's summary and conclusion

Conclusions:
The LD50 was considered to be 1460 mg/kg bw.