Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Identified in ECHA review article, no reference given, full literature article unable to be located.
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Reference
Reference Type:
publication
Title:
Pharmacodynamie. - Sur la toxicite des acides phtaliques.
Author:
Caujolle M.F., Meynier D.
Year:
1958
Bibliographic source:
C. R. Academie des Sciences, 246, 851-852

Materials and methods

Principles of method if other than guideline:
Method not determined: reference not located
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzoic acid
EC Number:
200-618-2
EC Name:
Benzoic acid
Cas Number:
65-85-0
Molecular formula:
C7H6O2
IUPAC Name:
benzoic acid

Test animals

Species:
mouse

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
other: isotonic saline

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
1 460 mg/kg bw

Applicant's summary and conclusion

Conclusions:
The LD50 was considered to be 1460 mg/kg bw.