Registration Dossier
Registration Dossier
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EC number: 200-618-2 | CAS number: 65-85-0
Health surveillance data
Administrative data
- Endpoint:
- health surveillance data
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Insufficient details available to make a reliability assessment.
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- publication
- Title:
- Influence of benzoic acid and benzoates on digestion and health.
- Author:
- Wiley HM, Bigelow WD
- Year:
- 1 908
- Bibliographic source:
- Bulletin 84, Part IV. Bureau of Chemistry, US Department of Agriculture [cited in US FDA, 1972a].
Materials and methods
- Principles of method if other than guideline:
- Method not determined: reference not located
Test material
- Reference substance name:
- Benzoic acid
- EC Number:
- 200-618-2
- EC Name:
- Benzoic acid
- Cas Number:
- 65-85-0
- Molecular formula:
- C7H6O2
- IUPAC Name:
- benzoic acid
- Details on test material:
- No data given
Constituent 1
Method
- Type of population:
- general
- Ethical approval:
- confirmed and informed consent free of coercion received
- Details on study design:
- Volunteers given 1000, 1500, 2000, or 2500 mg/day for 5 days each.
Results and discussion
- Results:
- Marked symptoms, signs of discomfort, and malaise (nausea, headache, weakness, burning and irritation of oesophagus) were reported.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
