Registration Dossier
Registration Dossier
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EC number: 200-618-2 | CAS number: 65-85-0
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
In a study on an aquatic ecosystem after exposure to the test substance (14C-labelled), radioactivity was recovered in the tested organisms (Water flea, green filamentous algae, snails, mosquito larvae and mosquito fish) after 24 hours. Most of the radioactivity present was identified as beeing metabolites of the test substance. This is indicative for rapid metabolism of the test substance when entering aquatic organisms. The bioaccumulation is expected to be low, which is also seen in several other studies on algae and in fish (Mallhot 1987, Freitag 1985). No BCF could be derived and therefore a calculation based on the logKow will be used in a worst case approach.
Key value for chemical safety assessment
Additional information
The results are insufficient to derive a BCF, but based on the the information available, it can be concluded that the BCF is expected to be low. In addition according to REACH Annex IX section 9.3.2 Column 2 this study can be waived if the substance has a low potential for bioaccumulation (for instance a log Kow <3). The Log Kow of the test substance was calculated as 1.88 by EPA's tool "KOWWIN Program (v1.67)", which indicate low potential for bioaccumulation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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