Registration Dossier

Environmental fate & pathways

Biodegradation in water and sediment: simulation tests

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Description of key information

The key study (Bouwer and McCarty, 1985) reported degradation of 22% in the sterile control and 91% in the seeded culture at 17 days. The methodology used was similar to the OECD 303B guideline (Simulation Test - Aerobic Sewage Treatment B.Biofilms). No half-life for the registered substance was reported.

Key value for chemical safety assessment

Additional information

Bouwer and McCarty, 1985, was selected as the key study for this endpoint as it was the most reliable study available. The study methodology was similar to the OECD 303B guideline (Simulation Test - Aerobic Sewage Treatment B.Biofilms), due to the limited data available on methodology it was not possible to detect deviations from the test guideline. Although no half-life was reported the registered substance was reported to reach 22% degradation in the sterile controls and 91% in the seeded culture at 17 days.

Bouwer et al, 1988, is presented as supporting information only. The registered substance reached 99% degradation in a methanogenic environment in <2 weeks.