Registration Dossier

Administrative data

Endpoint:
explosiveness
Type of information:
other: Expert Statement
Study period:
2008-06-10
Reliability:
1 (reliable without restriction)
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:
Cross-referenceopen allclose all
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
other: Expert Statement
Title:
Unnamed
Year:
2008
Report date:
2008

Materials and methods

Principles of method if other than guideline:
NA
GLP compliance:
no

Test material

Constituent 1
Details on test material:
NA

Results and discussion

Any other information on results incl. tables

NA

Applicant's summary and conclusion

Conclusions:
Explosive properties can be excluded based on the chemical structure of the test item.
Executive summary:

The test method for the determination of the explosive properties of a substance as described for solid materials in Test Guideline A.14 of EC Directive 92/69/EEC was replaced by a theory based evaluation.

Explosive properties are not expected, if an organic molecule does not contain oxygen, chlorine or fluorine, or if the molecule does contain oxygen, chlorine or fluorine, but these elements are chemically bonded to carbon or hydrogen, only.

Thus, based on the chemical structure of AVE 5530 EVA-KET no explosive properties are expected. All the oxygen atoms, as well as the fluorine atom are bound to carbon atoms only and thus, the molecule as a whole does not exhibit explosive properties. This argumentation is in line with recommendations of the German Authorities (BAuA) for the notification dossiers / data sets of ELINCS substances.

In conclusion, based on the chemical structure of AVE 5530 EVA-KET and individual structural components of the molecule, explosive properties are not expected.