1-ol, [[4-[(3-aminophenyl)amino]-6-chloro-1,3,5-triazin-2-yl]amino]-2-[(E)-2-ylazo]-, polysulfonate, polynaphthen, sodium salt (1:?), diazotized, reaction products with 2-[(aminophenyl)sulfonyl]ethyl hydrogen sulfate, 1-naphthalenol, 8-amino- (1:1), polysulfonates, sodium salts and 2,4,6-trihalogeno-1,3,5-triazine

Endpoint summary

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion

Endpoint conclusion:

no adverse effect observed (not sensitising)

Additional information:

The animals did not show any clinical signs during the course of the study and no cases of mortality were observed. A test item is regarded as a sensitiser in the LLNA if the exposure to one or more test concentration resulted in 3-fold or greater increase in incorporation of 3HTdR compared with concurrent controls, as indicated by the Stimulation Index (S.I.). The estimated concentration of test item required to produce a S.I. of 3 is referred to as the EC3 value. In this study Stimulation Indices of 1.31, 1.65 and 1.53 were determined with the test item at concentrations of 5, 10, and 20% in ethanol:deionised water (30+70). The EC3 value could not be calculated, since none of the tested concentrations induced an S.I. greater than 3.

Migrated from Short description of key information:
The test item FAT 40840/A TE was found to be not a skin sensitiser under the described conditions (OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay (LLNA) in Mice

Justification for classification or non-classification

FAT 40840/A E is not classified since the result of the study lies outside the classification criteria