Registration Dossier
Registration Dossier
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EC number: 448-050-6 | CAS number: 444065-11-6
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (48 h) > 0.019 mg/L (mean measured concentration) (ISO 6346)
Key value for chemical safety assessment
Additional information
The short-term toxicity of 2-(4-tert-butylphenyl)-6-cyano-5-[bis(ethoxycarbonylmethyl)carbamoyloxy]-1 H-pyrrolo[1 ,2-b][1 ,2,4]triazole-7-carboxylic acid-2,6-di-tert-butyl-4-methyl-cyclohexyl ester
(UC-141) to aquatic invertebrates was investigated in a study by Bouwman (2004), conducted according to ISO Guideline 6341 under GLP conditions. A static limit test was performed in which 20 daphnids were exposed to a filtrate of a solution prepared at 100 mg/L (nominal). Immobility was recorded after 24 and 48 hours, and the test concentration was verified by analytical determination. After 48 hours no immobilisation or other adverse effects were reported, and therefore an EC50 could not be determined and it is considered to be > 0.019 mg/L (mean measured concentration).
In conclusion, UC-141 was not acutely toxic to aquatic invertebrates under the tested conditions.
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