Registration Dossier
Registration Dossier
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EC number: 448-050-6 | CAS number: 444065-11-6
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
LC50 (96 h) > 0.015 mg/L (mean measured concentration) (ISO 7346-1)
Key value for chemical safety assessment
Additional information
The short-term toxicity of 2-(4-tert-butylphenyl)-6-cyano-5-[bis(ethoxycarbonylmethyl)carbamoyloxy]-1 H-pyrrolo[1 ,2-b][1 ,2,4]triazole-7-carboxylic acid-2,6-di-tert-butyl-4-methyl-cyclohexyl ester
(UC-141) to fish was determined in a study by Bouwman (2004). This test was conducted according to ISO Guideline 7346-1, under GLP conditions. A limit test was performed in which the test organisms (Cyprinus carpio) were exposed for 96 hours to a filtrate of a solution prepared at 100 mg/L (nominal, verification of test concentration was performed by HPLC analysis). No mortality or other adverse effects could be observed at the end of the exposure period and therefore, a LC50 value could not be calculated and it is considered to be > 0.015 mg/L (mean measured concentration).
In conclusion, UC-141 was not acutely toxic to fish under the tested conditions.
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